Question 1
A 18 year old male presents with multiple grey ulcers in his buccal mucosa, sore throat, difficulty swallowing and multiple vesicles on his palms and soles. Which of the following is the most likely diagnosis?
(A) parvovirus B19
(B) cocksackie virus
(C) echovirus
(D) erythema multiform
(E) herpes simplex virus
B: cocksackie virus, also known as hand foot and moth disease is typified by the clinical presentation mentioned in the stem. Group A, type 16 is the most commonest. Rarely, encephalitis, meningitis or myocarditis may develop. Treatment is usually supportive. JAMA Dermatol 2013; 149:1419.
Question 2
A 43 year old female is 4 months post orthotopic liver transplantation for Hepatitis B and NASH cirrhosis. He has had bloody diarrhoea and increasing oxygen requirements. Just recently he has complained of deteriorating vision. The following image is seen on fundoscopy
A 18 year old male presents with multiple grey ulcers in his buccal mucosa, sore throat, difficulty swallowing and multiple vesicles on his palms and soles. Which of the following is the most likely diagnosis?
(A) parvovirus B19
(B) cocksackie virus
(C) echovirus
(D) erythema multiform
(E) herpes simplex virus
B: cocksackie virus, also known as hand foot and moth disease is typified by the clinical presentation mentioned in the stem. Group A, type 16 is the most commonest. Rarely, encephalitis, meningitis or myocarditis may develop. Treatment is usually supportive. JAMA Dermatol 2013; 149:1419.
Question 2
A 43 year old female is 4 months post orthotopic liver transplantation for Hepatitis B and NASH cirrhosis. He has had bloody diarrhoea and increasing oxygen requirements. Just recently he has complained of deteriorating vision. The following image is seen on fundoscopy
What is the most likely diagnosis?
(A) CMV retinitis
(B) HSV retinitis
(C) HIV retinitis
(D) Anterior Ischaemic Optic Neuritis
(E) Diabetic retinopathy
A: picture courtesy of wikipedia.
Question 3
What species of mosquito transmit the Dengue virus?
(A) Anophales spp.
(B) Aedes spp.
(C) Culex spp.
(D) Monsonia spp.
(E) Udaya spp.
B. Typically the infection is spread by Aedes aegypti mosquito, which is a day time feeder. Other aedus spp can also transmit the virus, such as A. albopictus. Lancet 352 (9132), 971 – 977
Question 4
What family of virus is responsible for Dengue?
(A) Flavivirus
(B) Lentivirus
(C) Herpes virus
(D) Enterovirus
(E) Alpha virus
A. Lancet 352 (9132), 971 – 977
Question 5
A patient who has returned from Sri Lanka 21 days ago presents with fevers, arthralgias, diarrhoea and shortness of breath. He has a non specific erythematous rash distributed throughout his trunk. Based on known incubation period and symptomatology, which of the following infections is this patient NOT likely to have
(A) Malaria
(B) Typhoid fever
(C) Dengue
(D) EBV
(E) Hepatitis A
C: The incubation period for dengue use 3 – 14 days, classically 4 – 7 days. Therefore he should have manifested symptoms earlier since his return from Sri Lanka. Lancet 352 (9132), 971 – 977
Question 6
Relative bradycardia is a feature in all of the following infections EXCEPT?
(A) Typhoid fever
(B) Dengue Fever
(C) Legionnaire’s disease
(D) Chlamydia spp pneumonia
(E) Malaria
E. However before attributing a relative bradycardia to infection, it is imperative that the patient does not have a cardiac pacemaker and is not on medications that can cause bradycardia. Journal of Infection 33(3), 185 – 91
Question 7
What family of virus does Ebola belong to?
(A) Lentivirus
(B) Retrovirus
(C) Flavivirus
(D) Filovirus
(E) Arbovirus
D: N Engl J Med 2014; 371:2054-2057
(A) CMV retinitis
(B) HSV retinitis
(C) HIV retinitis
(D) Anterior Ischaemic Optic Neuritis
(E) Diabetic retinopathy
A: picture courtesy of wikipedia.
Question 3
What species of mosquito transmit the Dengue virus?
(A) Anophales spp.
(B) Aedes spp.
(C) Culex spp.
(D) Monsonia spp.
(E) Udaya spp.
B. Typically the infection is spread by Aedes aegypti mosquito, which is a day time feeder. Other aedus spp can also transmit the virus, such as A. albopictus. Lancet 352 (9132), 971 – 977
Question 4
What family of virus is responsible for Dengue?
(A) Flavivirus
(B) Lentivirus
(C) Herpes virus
(D) Enterovirus
(E) Alpha virus
A. Lancet 352 (9132), 971 – 977
Question 5
A patient who has returned from Sri Lanka 21 days ago presents with fevers, arthralgias, diarrhoea and shortness of breath. He has a non specific erythematous rash distributed throughout his trunk. Based on known incubation period and symptomatology, which of the following infections is this patient NOT likely to have
(A) Malaria
(B) Typhoid fever
(C) Dengue
(D) EBV
(E) Hepatitis A
C: The incubation period for dengue use 3 – 14 days, classically 4 – 7 days. Therefore he should have manifested symptoms earlier since his return from Sri Lanka. Lancet 352 (9132), 971 – 977
Question 6
Relative bradycardia is a feature in all of the following infections EXCEPT?
(A) Typhoid fever
(B) Dengue Fever
(C) Legionnaire’s disease
(D) Chlamydia spp pneumonia
(E) Malaria
E. However before attributing a relative bradycardia to infection, it is imperative that the patient does not have a cardiac pacemaker and is not on medications that can cause bradycardia. Journal of Infection 33(3), 185 – 91
Question 7
What family of virus does Ebola belong to?
(A) Lentivirus
(B) Retrovirus
(C) Flavivirus
(D) Filovirus
(E) Arbovirus
D: N Engl J Med 2014; 371:2054-2057
